This multiple ascending dose study will evaluate safety and tolerability after repeated ascending doses of AZD2624
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Masking
QUADRUPLE
Enrollment
30
Research Site
Kanagawa, Japan
To assess the safety and tolerability of multiple ascending oral doses of AZD2624 in young healthy male Japanese subjects compared to placebo by assessment of adverse events, vital signs, physical examinations, laboratory parameters, ECGs and EEGs
Time frame: All assessments are made at each visit, at least daily, during the study.
To evaluate and characterize the pharmacokinetics of AZD2624 and its metabolites when given orally in multiple ascending doses of AZD2624 to young healthy male Japanese subjects by assessment of drug concentration in plasma
Time frame: Blood samples will be taken before and after study drug administration.
Identification of genes that influence the disposition, efficacy, safety and tolerability of AZD2624
Time frame: A single blood sample will be obtained
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