Evaluation of Immunogenicity, Reactogenicity and Safety of Herpes Simplex (gD) Candidate Vaccine With/Without Adjuvant

Inclusion Criteria: * Between 18 and 40 years of age * Written informed consent * Female volunteers must be using contraceptive and should avoid becoming pregnant for the duration of this study. * Good clinical condition as evidenced by history taking and physical examination Exclusion Criteria: * History of persistent hepatic, renal, cardiac or respiratory diseases. * Clinical signs of acute illness at the time of entry into the study. * Seropositive for antibodies against the human immunodeficiency virus (HIV). * Pregnancy, lactation. * Treatment with corticosteroids or immunomodulating drugs. * Simultaneous participation in another clinical trial. * Any previous history of allergy. * Any concomitant vaccination or administration of immunoglobulin during the study period. * Any abnormal laboratory value among the tests performed at screening