The purpose of this study is to determine whether ezetimibe in association with statins is more effective than statins alone on postprandial lipemia in type 2 diabetic patients.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
13
Department of Clinical and Experimental Medicine, Federico II University Hospital,
Naples, Naples, Italy
Incremental AUC after a fat-rich meal of cholesterol concentration in chylomicron and VLDL fractions
Time frame: 6 weeks
Incremental AUC after a fat rich-meal of apo B48 concentration- marker of the number of intestinally derived lipoproteins- in chylomicron and VLDL
Time frame: 6 weeks
Fasting LDL concentration
Time frame: 6 weeks
Cholesterol/triglyceride ratio in postprandial chylomicrons and VLDL fractions.
Time frame: 6 weeks
Postprandial LDL size
Time frame: 6 weeks
Concentration and Composition of different lipoprotein subclasses in the fasting condition.
Time frame: 6 weeks
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