Immune Response and Cytomegalovirus in Intensive Care Unit (ICU) Patients

Assistance Publique Hopitaux De Marseille29 enrolled

Overview

This prospective study evaluate the immune status of patients admitted in ICU.CMV remains dormant in the body, but in people with immune deficiency, CMV could reactivate and cause life-threatening pneumonia.

Candidates will be screened with medical history and blood tests.Then, 2 groups of 20 patients (with or without CMV reactivation) matched for CMV status will be compared for their immune system against CMV.

Study Type

INTERVENTIONAL

Masking

NONE

Enrollment

Conditions

Cytomegalovirus Infection

Interventions

Sampling of blood, phenotypic analysis sub-populations NK by cytometric of stream in multiple markingsOTHER

Sampling of blood

Sampling of blood, phenotypic analysis sub-populations NK by cytometric of stream in multiple markingsOTHER

Sampling of blood

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age more than 18-year-old * Informed consent Exclusion Criteria: * minors, * pregnant or lactating women, * adults under guardianship, * immunosuppression at the entrance to resuscitation, * AIDS

Locations (1)

Hôpital de Sainte Marguerite- Service de Réanimation Médicale

Marseille, France

Outcomes

Primary Outcomes

Bring to light the quantitative and qualitative immunological modifications of the present cells NK before the arisen of an infection to CMV

Time frame: 24 months

Secondary Outcomes

Bring to light the quantitative and qualitative immunological modifications of cells NK in the consequences of an infectious shock

Time frame: 24 months

Data from ClinicalTrials.gov

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