Comparison of Low and High Ligation in the Rectal Cancer

Wakayama Medical University100 enrolled

Overview

The purpose of this study is to evaluate the defecatory function when nerve fibers around the inferior mesenteric artery(IMA) and left colic artery(LCA) are preserved(so called low ligation ) or not(high ligation) in the rectosigmoid and rectal cancer surgery.

Fecal incontinence after anterior resection are often observed. Whether or not postoperative bowel function is influenced by the preservation of nerve fibers around the root of IMA and LCA (low ligation) is still unknown. So in this randomized controlled trial, we evaluate the efficacy of low ligation in terms of the bowel function.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

100

Conditions

Rectal Cancer

Interventions

preservation of nerve fibers around IMAPROCEDURE

low ligation

resection of nerve fibers around IMAPROCEDURE

high ligation

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * On the basis of whether anterior resection was anticipated at WMUH for rectosigmoid and rectal cancer, and appropriate informed consent was obtained. Exclusion Criteria: * Patients who could not respond to medical interview for own bowel function * Patients without an informed consent

Locations (1)

Wakayama Medical University, Second Department of Surgery

Kimiidera, Wakayama, Japan

Outcomes

Primary Outcomes

Assessment of bowel function

Time frame: 1 year

Secondary Outcomes

comparison of leakage rate

Time frame: 2 weeks

Data from ClinicalTrials.gov

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