A Study of MDX-1106 to Treat Patients With Hepatitis C Infection

Inclusion Criteria: * Infection with hepatitis C genotype 1 or mixed hepatitis C genotype; * Asymptomatic or nearly asymptomatic from hepatitis C; * Previous therapy with interferon and ribavirin or peginterferon and ribavirin without an SVR or relapsed following an SVR;or Interferon naive subjects * Chronically infected (at least 6 months since diagnosis) HCV-positive subjects; * No evidence of bridging necrosis or cirrhosis; * Liver biopsy within the last 2 years Exclusion Criteria: * Acute hepatitis C infection * History of prior malignancy, acquired or inherited immunodeficiency or autoimmune disease either documented or anecdotal;