This study will evaluate the efficacy of SBR759 compared to sevelamer HCl in lowering serum phosphate levels in Chronic Kidney Disease patients on hemodialysis
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
321
Starting dose of 1g or 1.5g tid, with an increase of 1g tid every 2 weeks until serum phosphate level fall below target.
0.8 g tid
1.5 g tid
Responder rates in target serum phosphate levels at 12 weeks Evaluate efficacy of SBR759 compared to sevelamer HCl at 12 weeks
Time frame: Time Frame: 12 weeks + 12 months
Responder rates in target patients with serum calcium-phosphate levels at 12 weeks/12 months
Time frame: Time Frame: 12 weeks / 12 months
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1.6 g tid
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Chula Vista, California, United States
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La Mesa, California, United States
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Whittier, California, United States
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Denver, Colorado, United States
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North Chicago, Illinois, United States
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Peoria, Illinois, United States
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Mishawaka, Indiana, United States
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Baltimore, Maryland, United States
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Fall River, Massachusetts, United States
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Springfield, Massachusetts, United States
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