Cardiovascular Risk in Growth Hormone Deficient Young Adult Males After Completing Growth Hormone Therapy

Growth Hormone Deficient Inclusion Criteria: * Males, 18-25 years old * Completed growth hormone therapy approximately 3-5 years prior to study enrollment * History of multiple pituitary hormone deficiencies or growth hormone stimulation test \<7 at initiation of growth hormone therapy Healthy Control Inclusion Criteria: * Males, 18-25 years old * No confirmed endocrine diagnosis including Diabetes and thyroid disorders * BMI - z-score within 2 SD of mean Exclusion Criteria: * Known risk factors for cardiovascular disease (eg tobacco use, hypertension, diabetes) * Family history of early cardiovascular disease (myocardial infarction or stroke \<55years of age) in first degree family members * Any implanted device * Medication known to interfere with glucose or lipid metabolism or to influence blood pressure * Chronic organ illness (eg severe asthma, hepatic or nephritic conditions)