Corticotherapy accelerates maternal postpartum recovery in women with class I HELLP syndrome. The benefit of faster and better recovery would be observed in fewer complications, less utilization of blood products and shorter hospital stay.
Patients with Class I HELLP Syndrome will be recruited for use os dexamethasone or placebo in the puerperium. Effects such as clinical course (blood pressure and diureses), laboratorial behaviour and complications will be compared. Duration of hospitalization will also be accessed.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
400
Dexamethasone, 10mg (2mL), intravenous, every 12 hours, for 48 hours
Saline solution, 2 mL, intravenous, every 12 hours, for 48 hours
dexamethasone, 10mg, 2 mL, intravenous solution, every 12 hours , for 48 hours
Instituto Materno Infantil Prof. Fernando Figueira
Recife, Pernambuco, Brazil
severe maternal morbidity
42 days after delivery
Time frame: postpartum
hospital stay duration
Time frame: postpartum
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