Lymphadenectomy In Ovarian Neoplasms

Inclusion Criteria: * Primary diagnosis of invasive epithelial ovarian cancer FIGO stage IIB-IV (IV only if resectable metastasis in pleura, liver, spleen, and/or abdominal wall) * Macroscopic complete resection * Age: 18 - 75 years * Patients who have given their signed and written informed consent * Good performance status (ECOG 0/1) Exclusion Criteria: * Non epithelial ovarian malignancies and borderline tumors * Intraoperative clinically suspicious lymph nodes (bulky nodes) * Secondary invasive neoplasms in the last 5 years (except synchronal endometrial carcinoma FIGO IA G1/2, non melanoma skin cancer, breast cancer T1 N0 M0 G1/2) or with any signs of relapse or activity. * Recurrent ovarian cancer * Prior chemotherapy for ovarian cancer or abdominal/pelvic radiotherapy * Diseases of the lymph system (including lymph edema of unknown origin) * Clinical relevant dysfunctions of blood clotting (including medicamentous conditioned reasons, e.g. ASS, if not stopped at least 7 days prior to surgery) * Any significant medical reasons, age or performance status that will not allow to perform the study procedures (estimation of investigator) * Prior retroperitoneal lymph node dissection (systematic or sampling) * Pregnancy * Dementia or significantly altered mental status that would prohibit the understanding and giving of informed consent * Any reasons interfering with regular follow-up