Investigate the Effect of Neramexane Mesylate IR Tablet on Driving Fitness and Capability to Operate Machines in Healthy Volunteers

Inclusion Criteria: * healthy volunteers, female and male * age 21 - 50 * BMI 18 - 30 kg/m2 * experienced drivers with a valid driver's license and at least 3 years of driving practice Exclusion Criteria: * any clinically relevant finding on physical examination affecting the study objectives * clinically relevant abnormalities in the ECG laboratory values * history or present evidence of clinically relevant metabolic, renal, hepatic, pulmonary or cardiovascular disease, CNS disorders, or disturbance of bleeding diagnosis of malignancy * females who are pregnant or breastfeeding