Use of Cold and Compression Therapy With Total Knee Replacement Patients

Inclusion Criteria: * At least 18 but no more than 85 years of age * Body Mass Index not greater than 40 * Diagnosis of osteoarthritis of the knee * Medically cleared for total knee replacement surgery * Physically and mentally able and willing to participate in and follow the study protocol and schedule * Able and willing to have all postoperative physical therapy visits in a physical therapy clinic associated with the research site * Signed informed consent document for the study Exclusion Criteria: * Rheumatoid arthritis * Severe pitting edema in the ipsilateral limb * History of thrombophlebitis in lower extremities * An active systemic disease such as AIDS, HIV, hepatitis, etc. * Is immunologically suppressed or has received or is receiving steroids at any dose daily for more than one month within the last 12 months * Is pregnant or planning to become pregnant during the study period * Any condition that would contraindicate using the Game Ready * Currently enrolled in another clinical trial that could affect outcome of this study * Previously enrolled in this study