Immune Responses in Adults to Revaccination With ADACEL® 10 Years After a Previous Dose

Inclusion Criteria : * Received Tdap or Tdap-IPV vaccine in study TD9707 or TD9805. * Never previously received Tdap vaccine and has not received any tetanus-, diphtheria , or pertussis-containing vaccine in the past 10 years. * Participated in TD9707 or TD9805 but does not meet inclusion/ exclusion criteria or willing to undergo phlebotomy but not willing to receive Tdap (ADACEL®) vaccine. * Signed Institutional Review Board (IRB)-approved informed consent form * Able to attend all scheduled visits and to comply with all trial procedures * For a woman, a negative urine pregnancy test and the use of effective method(s) of contraception, or the inability to become pregnant Exclusion Criteria : * Any condition listed as a contraindication in the ADACEL® Canadian product monograph * Any condition which, in the opinion of the investigator, would pose a health risk to the subject or interfere with the evaluation of the vaccine * Chronic illness, at a stage that could interfere with trial conduct or completion, in the opinion of the investigator * Known or suspected congenital or acquired immunodeficiency, immunosuppressive therapy such as anti-cancer chemotherapy or radiation therapy within the preceding 6 months, or long-term systemic (injected or oral) corticosteroid therapy. Individuals on a tapering dose schedule of oral steroids lasting less than 7 days may be included in the trial as long as they have not received more than 1 course within the last 2 weeks prior to enrollment * Febrile illness (temperature ≥ 37.5°C \[99.5°F\]) at the time of inclusion * History of documented diphtheria, pertussis, or tetanus disease since participation in studies TD9707 or TD9805. Or history of documented diphtheria, pertussis, or tetanus disease in the last 10 years. * Known or suspected receipt of a diphtheria-, pertussis-, or tetanus-containing vaccine since participation in study TD9707 or TD9805. For Group 2, known or suspected receipt of a diphtheria-, pertussis-, or tetanus-containing vaccine in the last 10 years. * Receipt of any vaccine, other than influenza vaccine, in the 28-day period prior to Visit 1 or scheduled to receive any vaccine, other than influenza vaccine, in the period between Visit 1 and Visit 2. For influenza vaccine only, defer if received in the 14 days prior to enrollment or scheduled to receive prior to Visit 2. * Receipt of blood or blood-derived products in the past 3 months * Suspected or known hypersensitivity to any of the vaccine components, or a life-threatening reaction after previous administration of the vaccine or a vaccine containing the same substances * Unable to attend the scheduled visits or to comply with the study procedures * In females of childbearing potential, known pregnancy or positive serum/urine pregnancy test * Breast-feeding woman * Participation in another clinical trial investigating a vaccine, drug, medical device, or a medical procedure in the 4 weeks preceding enrollment. Planned participation in another clinical trial during the present trial period * Current alcohol or recreational drug use that may interfere with the subject's ability to comply with trial procedures * Thrombocytopenia, bleeding disorder, anticoagulation therapy contraindicating intramuscular (IM) vaccination * Subject deprived of freedom by an administrative or court order, or in an emergency setting, or hospitalized without his/her consent. * Other events which in the judgment of the investigator would preclude vaccination at the time of Visit 1 For Group 3 * History of documented diphtheria, pertussis, or tetanus disease since participation in study TD9707 or TD9805 * Known or suspected receipt of a diphtheria-, pertussis-, or tetanus-containing vaccine since participation in study TD9707 or TD9805.