Speech and Language Therapy After Stroke

University of Chicago34 enrolled

Overview

Our overall goal is to advance the state of functional brain imaging in aphasia, and then to apply the method to an intensive, imitation-based treatment for non-fluent aphasia.

Detailed information will follow in the next progress report.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Ischemic Stroke

Interventions

Imitate TherapyBEHAVIORAL

Imitation-based computer therapy

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: 1. Single ischemic infarction in the MCA territory involving the cerebral cortex (confirmed by CT or MRI) 2. Aphasia 3. Visual attention and language comprehension sufficient to perform imitation fMRI tasks 4. Right handed (prior to stroke) Exclusion Criteria: Exclusions to the study are people with cardiac pacemakers, claustrophobia, neurosurgical clips, or cognitive impairments too severe to permit cooperation with cognitive tasks in an MRI scanner.

Locations (2)

Solodkin/Small Brain Circuits Laboratory

Irvine, California, United States

University of California Irvine

Irvine, California, United States

Outcomes

Primary Outcomes

Changes in scores on Western Aphasia Battery

Time frame: Four months

Data from ClinicalTrials.gov

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