The purpose of this study is to investigate the safety and tolerability of multiple once daily ascending doses of AZD3199 in healthy men
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
27
Research Site
Lund, Sweden
Incidence and nature of Adverse Events
Time frame: Before, during and after dosing
Clinical significant abnormalities in ECG, pulse, blood pressure, lung function, temp, lab
Time frame: Before, during and after dosing
Pharmacokinetics
Time frame: Before, during and after dosing
Potassium and lactate concentrations
Time frame: Before, during and after dosing
Tremor, palpitations, heart rate, QTc, pulse and blood pressure and FEV1
Time frame: Before, during and after dosing
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high dose Dry powder for inhalation, o.d., 1+12 days