ProtectiScope CS Intended for Diagnostic and Therapeutic Colonoscopy

Inclusion Criteria: * Subject between the ages of 18 and 80 * Subject is indicated for screening colonoscopy * Subject is willing to sign informed consent form Exclusion Criteria: * Subject is suspected, based on radiographic or other clinical grounds, of suffering from one or more of the following: full or partial colonic obstruction; acute abdomen; gross hematochezia; severely ulcerated colon; diverticulitis; severe diverticulosis; toxic megacolon. * Subject has active cardiac problems and history of heart failure, severe pulmonary diseases renal failure (creatinine \>2) uncontrolled diabetes and any other illness judged by investigator to substantiate exclusion. * Subject has a history of significant other diseases. * Subject has a history of psychiatric disorders which would prevent compliance with study instructions * For female subjects, suspicion of pregnancy * Subject has received treatment with another investigational drug or device within the past 30 days