Treatment with MMF often results in adverse GI events, which can lead to dose reductions of MMF and decreased graft function. Enteric-coated mycophenolate sodium (MYFORTIC\*) was developed as an alternative formulation of MPA to improve upper GI tract side effects. An improvement in the severity of GI side effects could result in an increased tolerance to MPA and an improvement in patient quality of life. This study will use the GSRS to evaluate improvement in gastrointestinal symptoms.
This study will evaluate the change in the total gastrointestinal symptom rating scale (GSRS) score at baseline versus month 1,at baseline versus month 3 and at baseline versus month 6 after conversion from MMF to PRMYFORTIC\* .
Study Type
OBSERVATIONAL
Enrollment
59
Hôpital Maisonneuve-Rosemont
Montreal, Quebec, Canada
Evaluate the change in the total gastrointestinal symptom rating scale(GSRS) score at baseline vs 1 month, va 3 month and vs 6 month
Time frame: 1 month- 3 month-6 month
evaluate the change in the diarrhea GSRS subscale on a per patient basis
Time frame: at month 6
incidence of adverse events and serious events at months 3 an d6 will be evaluated
Time frame: month 3 and 6
Renal function and incidence of acute rejection
Time frame: 1-3-6 months
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