Incidence and Patterns of Nausea/Vomiting With Combined Chemotherapy and Radiation

Thomas Jefferson University40 enrolled

Overview

Questionnaire study to observe the incidence and pattern or nausea and vomiting in patients receiving combined chemotherapy and radiation. 83% of patients experience radiation therapy-induced vomiting; significant nausea and vomiting could develop with concurrent chemotherapy despite standard anti-nauseous medication prophylaxis.

Questionnaires will be answered daily on a weekly basis during period of radiation and chemotherapy.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Cancer of the Head and Neck Cancer of the Lung Cancer of the Esophagus Gastro-esophageal Junction Cancer

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Concurrent radiation and chemotherapy treatment * Aerodigestive malignancy Exclusion Criteria: * Other causes of vomiting (i.e.gastrointestinal obstruction...)

Locations (1)

Thomas Jefferson University

Philadelphia, Pennsylvania, United States

Outcomes

Primary Outcomes

Assess incidence and patterns of nausea and vomiting in patients undergoing concurrent chemotherapy and radiation

Time frame: week of treatment

Secondary Outcomes

Assess the impact of nausea and vomiting on the patients' daily functioning

Time frame: week of treatment

Study the incidence of mucositis and esophagitis

Time frame: week of treatment

Data from ClinicalTrials.gov

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