Does Coenzyme Q 10 Supplementation Reduce Muscle Pain Caused by Statins? (Cholesterol Lowering Medications)

Hadassah Medical Organization37 enrolled

Overview

The purpose of this study is to determine whether Coenzyme Q 10 supplementation will decrease the rate of Muscle Pain in patients with previous statin related Muscle Pain.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

Conditions

Statin Induced Myalgia

Interventions

Coenzyme Q 10DRUG

PO Coenzyme Q 10 120 mg QD

Placebo controlDRUG

po Placebo QD

Eligibility

Sex: ALLMin age: 20 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients treated for hyperlipidemia with a HMG-CoA reductase inhibitor (i.e. pravastatin, simvastatin rosuvastatin or atorvastatin) and reporting myopathic symptoms Exclusion Criteria: * Patients with other identifiable cause of myopathy. Patients with clinical evidence of hepatic, renal, or endocrine disease; coagulopathy; or other serious medical conditions will be excluded.

Locations (1)

Hadassah-Hebrew University Medical Center

Jerusalem, Israel

Outcomes

Primary Outcomes

1. The number of patients who tolerate statin at the initial dose. 2. The number of patients remaining on statin therapy. 3. Change in myalgia score.

Time frame: 4, 8, and 12 weeks

Data from ClinicalTrials.gov

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