To determine whether or not high frequency chest wall oscillation (in the form of the VestTM) is superior to regular asthma therapy in the management of children hospitalized with moderate to severe asthma.
A historically controlled pilot study was conducted in pediatric patients 18 months to 18 years of age hospitalized with a diagnosis of asthma or reactive airway disease and admitted to the pediatric intensive care unit. Upon receiving informed consent, patients were treated with HFCWO therapy via the VEST. The primary endpoint was time to readiness for discharge, lack of need for continued supportive care (e.g., intravenous fluid or oxygen), and bronchodilator treatments spaced at least four hours apart.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
43
15 minutes of HFCWO via the Vest 2-3 times daily
Winthrop University Hospital, Winthrop Pediatric Associates
Long Island City, New York, United States
Winthrop University Hospital
Long Island City, New York, United States
The Primary Endpoint Will be Time to Readiness for Discharge.
Days in the hospital prior to patient being clinically ready to discharge
Time frame: 30 days
Secondary Endpoint Total Hospital Length of Stay
Seconadary endpoint was Total Hospital length of stay
Time frame: 30 Days
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