Patients undergoing lung resection due to pulmonary cancer can be compromised in their postoperative period due to atrial fibrillation. A retrospective analysis performed at our institution indicates that 30 % of the population develope atrial fibrillation in the postoperative period. Amiodarone is known to diminish the occurence of postoperative atrial fibrillation after heart surgery, why this drug is chosen as a prophylactic agent for the mentioned population. Amiodarone is administrated twice a day for 5 days at a dose of 600 mg oral treatment after an initial loading bolus og 300 mg intravenously.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Enrollment
275
intravenous bolus of 300 mg oral treatment og 600 mg twice a day for five days
Aarhus University Hospital, Skejby
Aarhus, Denmark
Free of atrial fibrillation
Time frame: 31082009
Cost-benefit analysis of amiodarone prophylactic
Time frame: 31082009
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