Our aim is to evaluate the potential of a new laboratory method that measure sperm capacitation to predict fertilization of oocytes in patients that undergo IVF treatments
Capacitation is a physiologic process in which the sperm acquire the potential to fertilize oocytes. Capacitation can be measured, but the available technics are expensive, inaccurate and complex. A new method to evaluate sperm capacitation was developed in Bar Ilan University, Israel. We intend to measure the capacitation of semen that is used for fertilizing human oocytes in patients treated at the IVF unit at Assaf Harofeh Medical Center.By this, to evaluate the potential of the new method to predict human oocyte fertilization.If the method will be found valuable, it will enable to develop new drugs/methods that may improve sperm capacitation and by this to improve oocyte fertilization leading to more embryos, pregnancies and deliveries.
Study Type
OBSERVATIONAL
Enrollment
50
sperm capacitation measured at Bar Ilan University
sperm synthesis of G-actine to F-actine
sperm synthesis of G-actine to F-actine
Assaf Harofeh MC
Beer Yaacov, Zerifin, Israel
RECRUITINGFertilization rate of human oocytes in thr "routine" IVF Laboratory work
Time frame: One year
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