Study to Investigate the Effects of AZD6140 in Patients With Renal Impairment and in Healthy Volunteers

Inclusion Criteria: * Patients must have severe kidney disease * Subjects who are matched to the kidney disease patients in terms of weight, age, and sex must have normal kidneys * All women must be post-menopausal (no longer menstruating) or surgically sterile Exclusion Criteria: * Patients requiring dialysis * History of allergy to aspirin or clopidogrel * Have increased bleeding risk (for instance uncontrolled high blood pressure or a recent major injury) * Recent history of fainting or light-headedness