Anesthesia during uterine curettage is a problem. Paracervical block is used in general for such an operation, though, the anesthetic efficacy is incomplete. Propofol is the short-lasting intravenous anesthetic administrated popularly. Sevoflurane is a new inhalational anesthetic well-known for it's "easy come, easy go" property. The investigators hypothesized that propofol, sevoflurane and paracervical block had different anesthetic efficacy during uterine curettage. Which one is the optimal selection for such operation needed to be evaluated.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
150
Paracervical injection of 2% Lidocaine to block associated nociception input
Propofol 3mg/kg will be injected intravenously; 1 mg/kg will be added additionally for incomplete anesthesia
Sevoflurane 8% for anesthesia induction, 2-3% as the maintenance
Nanjing Maternal and Child Health Care Hospital
Nanjing, Jiangsu, China
Bispectral Index (BIS) value
Time frame: 0, 5, 10, 20, 30min after anesthesia
Intraoperative awareness
Time frame: 0, 5, 10, 20, 30min after anesthesia
Vital signs
Time frame: 0, 5, 10, 15, 20, 25, 30min after anesthesia
Arterial blood gas analysis
Time frame: 5min before operation; 1min and 5min after beginning of the operation
Pain intensity
Time frame: 0, 5, 10, 20, 30min after surgical procedures
Cortisol level
Time frame: 30min before operation; 1 and 5min during operation
Side effects
Time frame: 30min after operation
Uterine bleeding
Time frame: 0min after completion of the operation; 1 hour after the operation
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.