Wound Healing Abnormalities in Major Abdominal Surgery

Klinikum St. Georg gGmbH260 enrolled

Overview

This clinical observational study investigates the incidence of wound healing abnormalities in patients undergoing major abdominal surgery. Second aim of the study is, if wound healing deficits may be accompanied by abnormalities in blood coagulation parameters.

Study Type

OBSERVATIONAL

Enrollment

260

Conditions

Impaired Wound Healing Factor XIII Deficiency

Eligibility

Sex: ALLMin age: 18 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age \>= 18 years * Male or female * Informed consent * Major abdominal surgery Exclusion Criteria: * Pre-existing coagulation abnormalities * Pre-existing severe renal or liver failure * Chemo- or radiochemotherapy

Locations (1)

Klinikum St. Georg gGmbH

Leipzig, Saxony, Germany

Outcomes

Primary Outcomes

Incidence of wound healing abnormalities

Occurence of wound healing abnormalities within the first 28 days after surgery

Time frame: from baseline to postoperative day 28

Secondary Outcomes

Abnormalities in coagulation parameters

occurence of low platelets (\<60.000) or factor XIII \< 50% between the first and seventh postoperative day

Time frame: postoperative day 28

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.