Efficacy of BIO-K+ CL1285® Prophylaxis in the Prevention of Traveler's Diarrhea in Adults

Inclusion Criteria: * Male or female subjects over 18 years of age traveling to Mexico, Central America, South America and Caribbean Islands as direct destinations or on cruises to the same destinations. * The trips last a minimum of 7 days and a maximum of 21 days. * Women of child bearing capacity who are not pregnant at the moment of screening (pregnancy test done on-site) and agree to use an acceptable form of birth control for the duration of the study (e.g. Condom, oral contraceptives, etc.) are allowed to participate. Exclusion Criteria: * active diarrhea; * pregnancy; breastfeeding * 3 diarrheic episodes within 24 hours in the 15 days preceding the date of the departure; * antibiotic treatment during the last 15 days or ongoing treatment at the time of departure; * consumption of fermented milk, yogourt or probiotics probiotics in the 15 days preceding the date of the departure; * immunosuppressed state or any health condition being susceptible to decompensate during the study (including malignant hemo-pathologies, AIDS, bone marrow transplant or organ transplant). * active radiotherapy or chemotherapy as cancer treatment * the administration of an ETEC/cholera vaccine or any other diarrhea vaccine in the three months prior to study initiation * an active, non-controlled intestinal disease; * ileostomy, jejunostomy or colostomy * concomitant participation in another clinical trial * mental or other conditions, or language barriers rendering the subject unable to understand the nature, scope, and possible consequences of the study or complete the self-administered questionnaires; * subject unlikely to comply with protocol, e.g., uncooperative attitude, and unlikelihood of completing the study, * allergies to any ingredients in the study product (active product or placebo) * current use of illicit drug and alcohol abuse