An Efficacy and Safety Study of MORAb-003 in Platinum-Resistant or Refractory Relapsed Ovarian Cancer

Inclusion Criteria: * Diagnosis of non-mucinous epithelial ovarian cancer, including primary peritoneal and fallopian tube malignancies, measurable by CT or MRI scan assessed within 4 weeks prior to study entry * Must have evidence of relapse by CA-125 (2xUpper Limit of Normal) or radiographically within 6 months of most recent platinum-containing chemotherapy. At least one of the lines of chemotherapy must have included a taxane. * Must have been treated with debulking surgery and at least one line platinum-based chemotherapy; * Subjects may have received up to four additional lines of chemotherapy after they developed platinum-resistance. * Subjects must be candidate for repeat paclitaxel treatment Exclusion Criteria: * Clinical contraindications to use of paclitaxel, which include: 1. persistent Grade 2 or greater peripheral neuropathy 2. prior hypersensitivity reaction that persisted despite rechallenge with or without desensitization or resulted in bronchospasm or hemodynamic instability or was at least Grade 2 and resulted in medication discontinuation * Current diagnosis of epithelial ovarian tumor of low malignant potential (borderline carcinomas). Note: EOC with prior diagnosis of a low malignant potential tumor that has been surgically resected is acceptable provided the subject did * Prior radiation therapy is excluded with the exception that it is allowable only if measurable disease for ovarian cancer is completely outside the radiation portal * Known allergic reaction to a prior monoclonal antibody therapy or have any documented human anti-human antibody (HAHA). * Previous treatment with MORAb-003 (farletuzumab).