Effect of a Novel Sweetener on the pH of Dental Plaque.

Inclusion Criteria: * Good general health as evidenced by the medical history. * Male or non-pregnant, non-lactating females ages 18 to 75 inclusive. * Caries experience in the past year. * More than 5 decayed, missing, or filled teeth demonstrating a high caries experience. * Acidogenic plaque as demonstrated by a drop in pH to 5.7 or lower when challenged with sucrose rinse at the screening visit. * Willing to abstain from all oral hygiene procedures, brushing and flossing, for 48 hours prior to each test day and drink only water for the four (4) hours prior to each test. * Willing to abstain from the use of mouthwashes during the study. Exclusion Criteria: * Presence of orthodontic appliances. * Systemic conditions which could influence the pH of the oral cavity (i.e., diabetes, salivary gland disorders etc.). * Use of medications that would influence the pH of the oral cavity. Specifically, concomitant use of neuroleptics, atropine, chemotherapeutic agents, diuretics, antibiotics, antihistamines, decongestants, and muscle relaxants. Also, anticipated need for intermittent use of any medications in these classes or history of use during the 72 hours immediately prior to the screening visit. * Patients with aggressive periodontitis, acute necrotizing ulcerative gingivitis, or gross decay at discretion of Investigator. * Females who by self report are pregnant, lactating, planning to be pregnant during the study period, or women of childbearing potential who are unwilling to commit to the use of a medically approved form of contraception during the study period. * Exposure to any investigational agent within the 30 days prior to study visit 1 * Individuals requiring prophylactic antibiotics * Allergy or intolerance to food ingredients and products including artificial sweeteners.