The primary objective is to compare the incremental costs (direct and indirect) and benefits (healing outcomes, quality of life) of using foam silver dressing (Mepilex® Ag) to a Silver sulfadiazine 1% cream (Silvadene®) from the perspective of the health care provider. The secondary objectives are to investigate the safety, the tolerance and the performance on burn status including pain.
In- and/or out-patients at ten centers in the United States were included in this investigation. Subjects included were 5 years of age and older who suffered from partial thickness burns. Every patient was followed for 3 weeks.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Enrollment
100
LA County Hospital & USC Medical Center
Los Angeles, California, United States
The Burn Center, Washington Hospital Center
Washington D.C., District of Columbia, United States
Shands Burn Center, University of Florida
Gainesville, Florida, United States
Compare the Costs of Using the Interventions (Direct and Indirect)
The incremental cost-effectiveness ratio is calculated as the difference in total costs in each group divided by the difference in rate of full re-epithelialization (taken from the survival curve) at 20 days in each group (Δcosts/ Δeffects). Total costs were calculated based on the costs of primary and secondary dressings, silver sulphadiazine cream and estimated application, labor, supplies and pain medications. These costs were estimated from a representative sample of each population, across study facilities, using activity-based costing methods. The incremental cost-effectiveness ratio is interpreted as the price of additional health benefits. The ratio is supposed to be used by decision makers, in order for them to compare their willingness-to-pay for an additional health benefit with the pr
Time frame: August 2008-August 2009
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Joseph Still Burn Center
Augusta, Georgia, United States
UI Burn Treatment center
Iowa City, Iowa, United States
Cornell Medical Center
New York, New York, United States
Paul Silverstein Burn center
Oklahoma City, Oklahoma, United States
St Christopher's Hospital
Philadelphia, Pennsylvania, United States
Southwestern Regional Burn Center, Parkland Hospital
Dallas, Texas, United States
Department of Surgery
Seattle, Washington, United States