Influence of Plasma Rich in Growth Factors (PRGF) on Healing of Medial Collateral Ligament (MCL) Tear

Meir Medical Center50 enrolled

Overview

To evaluate the influence of Plasma Rich in Growth Factors (PRGF) on the healing process of medial collateral ligament (MCL) tear.

Autologous platelet-rich matrices may aid in the healing of ligaments \& tendons by promoting and accelerating tissue healing because of the release of growth factors including transforming growth factor (TGF)-beta1 and platelet-derived growth factor (PDGF) from platelet alpha-granules.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

MCL Tear

Interventions

Plasma Rich in Growth Factors (PRGF)BIOLOGICAL

injection onto injured area in ligament dose: 3-6mg

salineDRUG

injection of 6 cc of saline into injured area

Eligibility

Sex: ALLMin age: 18 YearsMax age: 40 Years

Medical Language ↔ Plain English

Inclusion Criteria: * age 18-40 years old * diagnosed MCL tear grade 2/3 Exclusion Criteria: * pregnancy * mental or physical disabilities

Locations (1)

Meir Medical Center

Kfar Saba, Israel

Outcomes

Primary Outcomes

time and efficiency of healing

Time frame: 1 year

Data from ClinicalTrials.gov

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