The aim of this study was to compare conservative versus aggressive strategy in patients with intermediate lesions with angiography guidance alone.
To investigate whether conservative revascularization using criteria of 70% diameter stenosis would be non-inferior to aggressive revascularization using criteria of 50% diameter stenosis in coronary intermediate lesions, we conducted the Conservative Revascularization versus Aggressive Revascularization for Coronary Stenting with Everolimus-Eluting Stents (SMART-CASE) trial.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
899
Stents were implanted in lesions with diameter stenosis \>50% and RD ≥2.25 mm and balloon angioplasty was performed in lesions with diameter stenosis \>50% and RD ≥2.0 mm and \<2.25 mm.
Stenting was performed only in lesions with diameter stenosis \>70% and reference diameter (RD) ≥2.25 mm
Samsung Medical Center
Seoul, South Korea
A composite of all cause death, MI, or any revascularization
Time frame: 1 year
All cause Death
Time frame: 1 years
Cardiac death
Time frame: 1 years
Myocardial infarction (Q-wave and non-Q wave)
Time frame: 1 years
Any revascularization
Time frame: 1 years
Stent thrombosis
Time frame: 1 years
Revascularization of target intermediate lesion
Time frame: 1 years
Target vessel failure
Time frame: 1 years
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