Effect of Effect of a Medicated Topical Therapy , Petrolatum, and No Treatment on Nocturnal Cough

Penn State University143 enrolled

Overview

This study seeks to subjectively evaluate whether a single application of Vicks® VapoRub® (VVR) ointment or a control ointment (petrolatum) will be superior to no treatment for control of nocturnal cough and congestion due to upper respiratory tract infection (URI) as rated by both parents and children.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

143

Conditions

Respiratory Tract Diseases

Interventions

Ointment containing camphor, eucalyptus oil, and mentholOTHER

One time use

Petroleum jellyOTHER

One time use

Eligibility

Sex: ALLMin age: 2 YearsMax age: 11 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Cough and congestion attributed to upper respiratory tract infection Exclusion Criteria: * Children with signs or symptoms of more serious or treatable disease * Presence of itchy, watery eyes or frequent sneezing * Tachypnea (respiratory rate \>95%ile) or labored breathing * Symptoms for 8 or more days * History of asthma in the past 2 years, chronic lung disease, or seizure disorder * History of an allergic reaction to camphor, menthol, eucalyptus, petrolatum, cedarleaf oil, nutmeg oil, thymol, turpentine oil, Over-the-counter medication containing VVR components

Locations (1)

Penn State Milton S. Hershey Medical Center

Hershey, Pennsylvania, United States

Outcomes

Primary Outcomes

Subjective assessment of cough and congestion symptoms

Time frame: 24 hours

Data from ClinicalTrials.gov

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