It's the aim of this study to investigate the impact of Right Ventricular (RV) lead position (RV-apex, His bundle area, RV-apex+His bundle area) in combination with individually optimized Left Ventricular (LV) lead placement and CRT timing on the outcome of cardiac resynchronization therapy (CRT).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
40
RV apical pacing lead, RV pacing lead at HIS bundle position, LV pacing lead implantation
Departement of Cardiology - Electrophysiology- Heart Centre Osnabrück - Bad Rothenfelde
Bad Rothenfelde, Germany
Improvement according to Packer's "Heart Failure Clinical Composite Respond"
Time frame: 12 months post implant
Intraoperative Increase in Left Ventricular dp/dt
Time frame: At Implant
Cardiopulmonary Capacity(Spiroergometry)
Time frame: 12 months
Change in B-type natriuretic Peptide (BNP)-Concentration
Time frame: 12 months
6 min walk test
Time frame: 12 months
QoL assessment("Minnesota Living with Heart Failure = MLHF)
Time frame: 12 months
12 channel ECG
Time frame: 12 months
2D-echo optimized EF
Time frame: 12 months
Complications and morbidity
Time frame: 12 months
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