How Improvement in Control of Diabetes Influences the Production of a Hormone Produced in the Gut Which Improves the Release and Action of Insulin.

The Royal Bournemouth Hospital74 enrolled

Overview

The study is aimed at Type 2 Diabetics who are taking Metformin, but whose Diabetes remains poorly controlled. There are two additional medications already in use, Glimepiride and Sitagliptin will be compared to assess levels of improvement in Diabetes control.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Type 2 Diabetes Mellitus

Interventions

GlimepirideDRUG

3mg oral tablet.

SitagliptinDRUG

100mg oral tablet.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Diabetes Mellitus * Currently on Metformin but poor glycaemic control, Exclusion Criteria: * Under 18 years of age

Locations (1)

Royal Bournemouth Hospital

Bournemouth, Dorset, United Kingdom

Outcomes

Primary Outcomes

Comparison of GLP-1 response at baseline and after 3 months treatment of both groups.

Time frame: 2 years

Data from ClinicalTrials.gov

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