Effects of Creatine Supplementation in Women With Knee Osteoarthritis and Fibromyalgia

University of Sao Paulo60 enrolled

Overview

The purpose of this study is to determine whether creatine associated or not to exercise training can improve physical performance in patients with knee osteoarthritis and fibromyalgia.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

Conditions

Knee Osteoarthritis Fibromyalgia

Interventions

Creatine supplementationDIETARY_SUPPLEMENT

Dextrose supplementationDIETARY_SUPPLEMENT

Eligibility

Sex: FEMALEMin age: 25 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Fulfill ACR criteria of knee osteoarthritis * Fulfill ACR criteria of fibromyalgia Exclusion Criteria: * Athletes * Drugs stable for at least three months before entering the study * No limitations to resistance training

Locations (1)

University of Sao Paulo School of Medicine

São Paulo, São Paulo, Brazil

Outcomes

Primary Outcomes

Physical function

Assessed by the timed-stands test

Time frame: 12 weeks

Secondary Outcomes

Strength

Assessed by the 1-repetition maximum test

Time frame: 12 weeks

Quality of life

health-related questionaires

Time frame: 12 weeks

Body composition

Assessed by DXA

Time frame: 12 weeks

Renal function

Assessed by 51Cr-EDTA

Time frame: 12 weeks

Data from ClinicalTrials.gov

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