Pharmacokinetics of Asacol 2.4 g/Day and Lialda 2.4 g/Day in Healthy Volunteers

Inclusion Criteria: * Males or females between 18 and 45 years of age, inclusive, at screening and in good general health based on medical history, physical examination, and laboratory evaluation; * If female, must be (as documented by patient reported medical history): * postmenopausal (at least 1 year without spontaneous menses), or * surgically sterile (tubal ligation or hysterectomy), or * using acceptable contraception \[e.g., sexual partner with non-reversed vasectomy (with azoospermia in 2 tests), 2 barrier methods (e.g., condom, diaphragm, or spermicide), or intra-uterine device\]; * Body mass index (BMI) between 18 and 32 kg/m2, inclusive; * Able to swallow the assigned study medication tablet whole; and, * Able to fulfill the requirements of the protocol and provide written informed consent. Exclusion Criteria: * History or presence of any condition or gastrointestinal (GI) surgery causing malabsorption or an effect on GI motility; * Any uncontrolled acute disease or major surgical operation requiring hospitalization within 1 month of screening; * History of diabetes, syncope, cardiovascular, hepatic, or renal disease; * Uncontrolled chronic diseases such as hypertension, systemic lupus erythematosus, or rheumatoid arthritis; * History of cancer within the last 5 years (except for basal cell carcinoma with a documented 6-month remission); * Any known enzyme-inducer, enzyme-inhibitor, or reported chronic exposure to enzyme-inducers such as paint solvents or pesticides within 30 days of treatment; * Any prescription drug or herbal remedy within 14 days prior to scheduled dosing