Renal Denervation in Patients With Refractory Hypertension

Medtronic Vascular35 enrolled

Overview

The purpose of this study is to investigate the clinical utility of renal denervation for the treatment of refractory hypertension.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Hypertension

Interventions

Renal DenervationDEVICE

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Systolic blood pressure of 160 mmHg or greater * On 3 or more antihypertensive medications * eGFR \>= 45 mL/min Exclusion Criteria: * Renal artery abnormalities * Known secondary hypertension attributable to a cause other than sleep apnea * MI, angina, CVA within 6 months * Type 1 diabetes * Others

Locations (3)

Prairie Heart Institute

Springfield, Illinois, United States

Hennepin County Medical Center

Minneapolis, Minnesota, United States

MetroHealth Medical Center

Cleveland, Ohio, United States

Outcomes

Primary Outcomes

Safety - complications associated with delivery and/or use of the Ardian Catheter, adverse renal events, electrolyte disturbances, hemodynamic events.

Time frame: Through 3 years

Secondary Outcomes

Physiologic response to renal denervation (e.g., blood pressure reduction)

Time frame: Through 3 years

Data from ClinicalTrials.gov

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