This is a Phase I, multicenter, open-label, dose-escalation study of single-agent D4064A administered by IV infusion to patients with recurrent or persistent epithelial ovarian cancer (EOC), primary peritoneal cancer (PPC), and fallopian tube cancer (FTC) who have previously received a platinum-containing regimen. The study will enroll up to 56 patients at up to six investigative sites in the United States.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
56
Investigational Site
New York, New York, United States
Investigational Site
Nashville, Tennessee, United States
Incidence and nature of dose-limiting toxicities (DLTs)
Time frame: Length of study
Incidence, nature, and severity of adverse events
Time frame: Length of study
Incidence of anti-D4064A antibodies
Time frame: Length of study
Changes in vital signs and clinical laboratory results
Time frame: Length of study
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.