This study is determine the effects of dietary calcium and phytate on zinc absorption.
Zinc absorption is tested from 2 days of consuming each of four diets with zinc-65 isotope, followed by retention monitoring in a whole body scintillation counter for 4 weeks. All four 4 experimental diets are tested with each subject, in randomized order, for a total of 16 weeks.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
17
Participants consumed diet containing 700 milligrams calcium and 440 milligrams of phytate for 4 weeks
Participants consumed diet containing 700 milligrams calcium and 1800 milligrams of phytate for 4 weeks
Participants consumed diet containing 1900 milligrams calcium and 440 milligrams of phytate for 4 weeks
United States Department of Agriculture Grand Forks Human Nutrition Research Center
Grand Forks, North Dakota, United States
Zinc Absorption
Retention of Zinc-65 was monitored for 28 days by whole body scintillation counting. The percentage of Zinc-65 absorbed was estimated from the y-intercept of the linear portion of a semilogarithmic retention plot of percent Zinc-65 retained versus time
Time frame: 16 weeks
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Participants consumed diet containing 1900 milligrams calcium and 1800 milligrams of phytate for 4 weeks