Safety and Efficacy Study of A Novel Ointment to Treat Plaque Type Psoriasis

Inclusion Criteria: 1. Male or female \>18 years of age at time of enrollment 2. The clinical diagnosis of stable plaque psoriasis 3. Two target plaques of similar severity * ≥ 5 cm2 but ≤ 100 cm2 computed by multiplying the greatest diameter of the plaque by the diameter of the plaque perpendicular to the greatest diameter * Bilaterally located (right/left) plaques on the arms or distinct plaques located on the trunk. Plaques located on the trunk must be separated by at least 10 cm and will be designated by the Investigator as either left/right or front/back or upper/lower * Overall target plaque severity score (OTPSS) of 2-4 (mild to moderate) with no more than a 1 point difference in the scores of the individual plaques 4. Normal or not clinically significant screening laboratory results 5. Willing and able to apply study drug as directed, comply with study instructions and commit to all follow-up visits 6. Ability to understand, agree to and sign the study Informed Consent Form (ICF) prior to initiation of any protocol related procedures Exclusion Criteria: 1. Any dermatological conditions that could interfere with clinical evaluations or any disease state or physical condition which might expose the patient to an unacceptable risk by study participation 2. Any underlying disease(s) or other dermatological conditions that require the use of exclusionary topical or systemic therapy (see below). 3. Known sensitivity to any of the components of the study medication 4. Spontaneously improving or rapidly deteriorating psoriatic plaques or pustular/exfoliative, guttate, erythrodermic or other non-plaque form of psoriasis 5. Concomitant use of topical or systemic therapies that might alter the course of psoriasis 6. Females of child bearing potential. Females must be post-menopausal or surgically sterile (oophorectomy). 7. Washout periods of: * Topical drugs that might alter the course of psoriasis: 2 weeks * Oral retinoids: 8 weeks * Non-retinoid systemic drugs that might alter the course of psoriasis: 4 weeks * PUVA: 4 weeks * UVB therapy: 4 weeks * Use of emollients/moisturizers on area(s) to be treated: 2 days to baseline visit 8. AIDS or AIDS related illness 9. Concurrent participation in another drug research study or within 30 days of enrollment 10. Use of lithium or hydroxychloroquine containing products (i.e. Plaquenil) 11. Use of a beta-blocking medication (i.e. propranolol) if the dose has not been stabilized for at least 3 months