A Study to Determine the Effect of WelChol Tablets on Cholesterol in Patients Who Have Been Taking Pravastatin for at Least 4 Weeks.

Inclusion Criteria: * Male or female \> or = to 18 years of age * On a stable dose of pravastatin * LDL-C \> or = to 100 mg/dL and \< or = 250 mg/dL * Triglycerides \< or = to 300 mg/dL * Women are not pregnant or breast-feeding or planning to become pregnant * Women have had a hysterectomy or tubal ligation, or who are post-menopausal or who practice an accepted method of birth control as specified in the protocol Exclusion Criteria: * BMI \> 40 kg/m2 * History of allergic or toxic reaction to colesevelam HCL * History of swallowing disorder * Any serious condition that would interfere with the conduct of the study