Inflammation in the adipose (fat) tissue is an important condition leading to metabolic derangements and cardiovascular disease in obese patients. n-3 polyunsaturated fatty acids exert anti-inflammatory effects and prevent adipose tissue inflammation in rodent obesity. This study tests the hypothesis that n-3 polyunsaturated fatty acids ameliorate adipose tissue inflammation in morbidly obese patients.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Enrollment
55
4g daily, 8 weeks
equivalent amount of fat as butter
Medical University of Vienna
Vienna, Austria
Adipose tissue inflammation
Time frame: Eight weeks of treatment
Metabolic control
Time frame: Eight weeks of treatment
Dependence of effects on Pparg polymorphisms
Time frame: Eight weeks of treatment
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