Clinical Biological and Pharmacological Factors Influencing Stroke Outcome

University Hospital, Lille550 enrolled

Overview

In a previous suty, we have demonstrated that prior transient ischemic attack, treatment lipid-lowering drug or physical activity are associated to a better outcome of stroke. The aim of the study is to understand the mechanisms of this preventive neuroprotection by establishing link between biomarkers and preventive and neuroprotective measures.To answer to the question, we conduct a cohort study of stroke patients.

In the cohort, the severity of stroke (NIHSS) will be correlated with : * clinical factors, * pharmacological factors, * biological factors (inflammatory markers, hemostasis...)

Study Type

OBSERVATIONAL

Enrollment

550

Conditions

Stroke

Eligibility

Sex: ALLMin age: 40 Years

Medical Language ↔ Plain English

Inclusion Criteria: * ischemic or hemorrhage stroke * hemispheric stroke * stroke dating from less 48h Exclusion Criteria: * non hemispheric stroke * malformative intracranial hemorrhage * traumatic intracranial hemorrhage * subarachnoidal hemorrhage

Locations (1)

Lille University Hospital - Service de Neurologie vasculaire

Lille, France

Outcomes

Primary Outcomes

severity of stroke measured by NIH severity score

Time frame: inclusion, day7, month3, year3

Secondary Outcomes

clinical, pharmacological and biological (metabolic, inflammation, hemostasis...) cognitive status

Time frame: inclusion and year3

Data from ClinicalTrials.gov

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