Coronary Artery Disease (CAD) in Postmenopausal Women

RWTH Aachen University100 enrolled

Overview

Aim of this study is the determination of a valid procedure for ischemia diagnositc in postmenopausal women.

In order to investigate which ischemia diagnostic presents which sensitivity and specificity for postmenopausal women, 100 consecutive patients presenting to our abmulance with stable angina pectoris and indication for myocardial szintigraphy will be enrolled in this study. An addidional stress-echocardiography and stress-MRI will be performed in this patients before they will reiceve their again routine coronay angiography. The different methods for ischemia diagnostic will be compared in order to determine the most valid method for this specific population.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

100

Conditions

Postmenopausal Women Stable Angina Pectoris

Interventions

stress-echocardiographyPROCEDURE

stress-echocardiography will be performed once using Adenosin (140 µg/kg/min over 6 Minutes) and a contrast agent (SonoVue)

stress-MRIPROCEDURE

stress-MRI will be performed once using Adenosin (140 µg/kg/min over 6 Minutes)and a contrast agent (Gadovist)

Eligibility

Sex: FEMALEMin age: 40 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Postmenopausal women presenting to the hospital with stable Angina pectoris complaints and an indication for myocardial szintigraphy Exclusion Criteria: * CABG * Pacemaker or other metal implants * Chronic bronchitis * Asthma bronchiale * Arterial Hypotension

Locations (1)

Department of Cardiology, RWTH Aachen University Hospital

Aachen, Germany

Outcomes

Primary Outcomes

comparision of different ischemia diagnostic methods

Time frame: before routine coronary angiography

Data from ClinicalTrials.gov

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