This is an open-label, randomized, parallel-group clinical study. The primary objective is to assess the difference in response rate between mometasone furoate cream 0.1% (once daily) vs fluticasone propionate cream 0.05% (twice daily) by the end of Day 4 and Day 8 in the management of Indian patients with localized psoriasis.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
245
Mometasone furoate cream 0.1% applied once daily
Fluticasone propionate cream 0.05% applied twice daily
Reduction in mean symptom scores for erythema, induration, pruritus, and scaling on Day 4.
Time frame: Day 4
Reduction in mean symptom scores for erythema, induration, pruritus, and scaling on Day 8.
Time frame: Day 8
Clinical evaluation of the change in disease status which would be defined as improvement by Day 4 relative to their severity at entry in treated areas.
Time frame: Day 4
Clinical evaluation of the change in disease status which would be defined as improvement by Day 8 relative to their severity at entry in treated areas.
Time frame: Day 8
Reduction in mean symptom scores for erythema, induration, pruritus, and scaling on Day 15.
Time frame: Day 15
Reduction in mean symptom scores for erythema, induration, pruritus, and scaling on Day 22.
Time frame: Day 22
Reduction in mean symptom scores for erythema, induration, pruritus, and scaling on Day 29.
Time frame: Day 29
Clinical evaluation of the change in treated areas relative to their severity at entry would also be evaluated on Day 15.
Time frame: Day 15
Clinical evaluation of the change in treated areas relative to their severity at entry would also be evaluated on Day 22.
Time frame: Day 22
Clinical evaluation of the change in treated areas relative to their severity at entry would also be evaluated on Day 29.
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Time frame: Day 29