Transcranial Magnetic Stimulation (TMS) for Treatment of Auditory Hallucinations

The University of New South Wales18 enrolled

Overview

Transcranial magnetic stimulation (TMS) involves the use of magnetic fields to non-invasively stimulate the brain. Studies overseas have suggested this may be an effective and safe treatment for auditory hallucinations in patients with schizophrenia. This is a sham-controlled, double-blind trial of TMS stimulation for the treatment of auditory hallucinations in patients with schizophrenia.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Auditory Hallucinations

Interventions

Transcranial magnetic stimulationDEVICE

Stimulation will be given daily at a particular site for three days a week

ShamDEVICE

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Over 18, with DSM-IV diagnosis of Schizophrenia and auditory hallucinations of clear external origins, refractory to pharmacotherapy and occurring at least 5 times per day. Exclusion Criteria: * Subjects with contraindications to TMS (e.g. epilepsy, pacemaker) or those with an unacceptably high risk (e.g. suicide risk) will be excluded from the study.

Locations (1)

School of Psychiatry

Sydney, New South Wales, Australia

Outcomes

Primary Outcomes

Daily Voices Ratings (Mental Health Research Institute, Victoria)

Time frame: Daily

Data from ClinicalTrials.gov

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