The aim of the study is to compare the outcomes of trans-catheter arterial embolization (TAE) and surgery as salvage therapy of peptic ulcer bleeding after failed endoscopic therapy.
The aim of the study is to examine the hypothesis that trans-catheter arterial embolization (TAE) is safer than and probably as effective as surgery in the control of bleeding from ulcers after failed endoscopic therapy. Patients with major arterial bleeding that cannot be stopped by endoscopic therapy will be randomly assigned to receive immediate TAE or surgery. Primary outcome will be death within 30 days of randomization. Secondary outcomes include recurrent bleeding after assigned treatment, need for additional intervention either in the form of interventional radiology or surgery, and post procedural morbidities.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
34
Trans-catheter arterial embolization
Surgery
Endoscopy Center, Prince of Wales Hospital
Hong Kong, China
Mortality within 30 days of randomization
Mortality within 30 days of randomization
Time frame: 30 days
Recurrent bleeding after assigned treatment
Recurrent bleeding after assigned treatment
Time frame: 60 days
The need for additional intervention either in the form of interventional radiology
The need for additional intervention either in the form of interventional radiology
Time frame: 60 days
Post procedural morbidities
Post procedural morbidities
Time frame: 60 days
The need for additional intervention either in the form of surgery
The need for additional intervention either in the form of surgery
Time frame: 60 days
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.