Pregnancy complications called PVP are mainly responsible for perinatal mortality. In these cases, the placenta is smaller and often the centre of thrombotic lesions. The estimation of the placenta volume by 3D ultrasound coupled with growth factors and D-Dimers measures could improve the understanding of these pathologies to optimize their detection.
Pregnancy complications called Placental Vascular Pathologies (PVP) are mainly responsible for perinatal mortality. In these cases, the placenta is smaller and often the centre of thrombotic lesions. The estimation of the placenta volume by 3D ultrasound coupled with growth factors and D-Dimers measures could improve the understanding of these pathologies to optimize their detection. Thus, the identification of predictive factors of the risk of occurrence or recurrence of PVP could allow us to propose a monitoring of patients at risk, to anticipate corticoids administration for the foetuses pulmonary maturation and perhaps later to adapt anti hypertensive and antithrombotic therapeutics.
Study Type
OBSERVATIONAL
Enrollment
40
biological markers evaluated : D-Dimer, sEPCR
Service de Gynécologie Obstétrique - CHU Saint-Etienne
Saint-Etienne, France
placental volume by 3D ultrasound and D-Dimers rate
Time frame: Week 12
EPCRs rate measurements
Time frame: Week 12
EPCRs rate measurements
Time frame: Week 16
EPCRs rate measurements
Time frame: Week 22
Occurrence or recurrence of PVP
Time frame: Week 12
Occurrence or recurrence of PVP
Time frame: Week 16
Occurrence or recurrence of PVP
Time frame: Week 22
placental volume by 3D ultrasound and D-Dimers rate
Time frame: Week 16
placental volume by 3D ultrasound and D-Dimers rate
Time frame: Week 22
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