CopiOs(TM) Bone Void Filler in the Post-Harvest Iliac Crest

Inclusion Criteria: * Patient is 18 years and older * Patient must be an appropriate candidate for iliac crest bone harvesting during a spinal fusion. * Patient must be skeletally mature. * Patient has signed an IRB approved Informed Consent and HIPAA compliant waiver. Exclusion Criteria: * Patient is suffering from any co-morbidities that would excessively increase the risk of surgery, including but not limited to pulmonary or cardiac conditions. * Patient is pregnant. * Patient has a severe degenerative bone disease. * Patient has systemic conditions which would affect bone or wound healing. * Patient is unwilling or unable to follow postoperative instructions or cooperate in a follow-up program. * Patient is suffering from mental illness, alcohol abuse or drug abuse. * Patient has known allergies to bovine collagen. * Patient has a history of multiple allergies. * Patient has infection at the surgical site. * Significantly impaired vascularity proximal to surgical site. * Sites are in direct contact with articular space. * Sites where stresses on void will exceed the load strength of fixation hardware. * Patient has hypercalcemia.