This study examines whether a permanent stimulation of the diaphragm improves left ventricular function in patients with severe heart failure following heart surgery.
Previous studies have shown that temporary stimulation of the diaphragm using an electrode to the phrenic nerve reduces electrical mechanical activation time (EMAT) and improves left ventricular function. This study examines whether patients with severe heart failure, who require permanent biventricular pacing after heart surgery, may benefit from an additional permanent electrode that stimulates the diaphragm. Heart function is assessed by echocardiography and acoustic cardiography (Audicor, Inovise Medical Inc., Portland, USA).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
33
Stimulation of the diaphragm using an electrode
Kantonsspital Luzern
Lucerne, Canton of Lucerne, Switzerland
Left ventricular ejection fraction
Time frame: One day
Brain natriuretic peptide (BNP)
Time frame: One day
6-minutes walking distance
Time frame: One day
NYHA functional class
Time frame: One day
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